Stem cell therapy: Differentiation potential of insulin producing cells from human adipose derived stem cells and umbilical cord MSCs

Diabetes mellitus is a huge burden for several countries. No matter type I or type II diabetes, the insufficient of insulin causes the dysfunction of regulating blood sugar and leads to hypoinsulinemia and life threatening ketoacidosis. To our knowledge, no effective treatment to cure diabetes and most diabetic patients still need to rely on the long-term injection of insulin. Herein, we summarized new finding and advantageous resource for regenerative medicine with the possibility to be employed in diabetes treatments. We also discuss the differentiation potentials of human adipose derived stromal cells (hADSCs) and human umbilical cord derived mesenchymal stem cells (hUCMSCs) and give rise to a new hope of treatment in the future.